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Dorzolamide hydrochloride
CAS No. 130693-82-2
Dorzolamide hydrochloride ( L-671,152 | MK-507 )
产品货号. M11227 CAS No. 130693-82-2
Dorzolamide Hcl(L671152 Hcl; MK507 Hcl) 是一种抗青光眼剂，是一种碳酸酐酶抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥300 | 有现货 |
|
| 10MG | ￥405 | 有现货 |
|
| 25MG | ￥494 | 有现货 |
|
| 50MG | ￥786 | 有现货 |
|
| 100MG | ￥1239 | 有现货 |
|
| 200MG | ￥1839 | 有现货 |
|
| 500MG | ￥3102 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Dorzolamide hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Dorzolamide Hcl(L671152 Hcl; MK507 Hcl) 是一种抗青光眼剂，是一种碳酸酐酶抑制剂。
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产品描述Dorzolamide Hcl(L671152 Hcl; MK507 Hcl) is an anti-glaucoma agent, which is a carbonic anhydrase inhibitor.(In Vitro):Component A, caused by an inward flux of CO2 and its subsequent hydration by CA-II, is blocked by Dorzolamide in a dose-dependent manner with an 50% inhibitory concentration IC50 of 2.4 μM (95% confidence interval: 0.5-10.85 μM).(In Vivo):Dorzolamide (3, 10, or 30 mg/kg/day, ip) synergized mitomycin C exhibits anti-tumor activity in EAC solid tumor models. Dorzolamide produces a dose-dependent decrease in the calculated ratio (relative value of 57.3±1, 25.5±1.8, and 24.3± 0.7 %, respectively).
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体外实验——
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体内实验——
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同义词L-671,152 | MK-507
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通路Membrane Transporter/Ion Channel
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靶点Carbonic Anhydrase
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受体Carbonic anhydrase I| Carbonic anhydrase II| Carbonic anhydrase IV
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研究领域Other Indications
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适应症——
化学信息
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CAS Number130693-82-2
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分子量360.9
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分子式C10H17ClN2O4S3
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纯度>98% (HPLC)
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溶解度Water: 14 mg/mL (38.79 mM)
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SMILESO=S(C(S1)=CC([C@@H](NCC)C[C@@H]2C)=C1S2(=O)=O)(N)=O.[H]Cl
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化学全称(4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Maren TH, et al. J Ocul Pharmacol Ther, 1997, 13(1), 23-30.
产品手册
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